- Director: Martín Deus
- Writer: Martín Deus
Lorenzo is a quiet teenager who lives with his parents and his younger brother in small city in the Argentinean Patagonia. One day, a family friend's son named Caíto moves south and settles in at Lorenzo's home. His family is going through difficult times and can't give much care to him. Caíto is very shy and hardly speaks. Lorenzo is supposed to help him feel at home. They become friends. They spend great amounts of time together. Although Lorenzo doesn't like sports, he puts up with Caíto's fascination for mountain biking. They share deep conversations too. They can be very different but they come to understand each other. It won't be long until everybody at home realizes Caíto is a difficult case. After a couple of days, Lorenzo's parents feel they've had enough. But then, Caíto makes a big confession to Lorenzo. He tells him the true reason why he was forced to leave his house. After that, Lorenzo takes charge of him so that his parents let him stay. He now has a secret to hold, a responsibility to take and a troublesome partner that will take him through new life experiences.
Mi Mejor amigo cuenta la insólita amistad entre Caíto, un enigmático rufián adolescente con prontuario incluido, y Lorenzo, un quinceañero con un excesivo sentido de la responsabilidad y un temor apabullante a quedarse solo. Ambientada en una pequeña ciudad de la Patagonia, la historia comienza cuando la vida familiar en casa de Lorenzo se ve revolucionada tras aceptar hacerse cargo por un tiempo de Caíto, el hijo de un amigo que está enfrentando algunos problemas en su casa. A raíz de esta convivencia forzada, Lorenzo se verá obligado a cuidar del nuevo huesped, a la vez que, involucrándose en sus locuras, terminará adentrándose en el ríspido y a veces desconcertante camino del autodescubrimiento.